High Powder ✓
Excessive flow rates may decrease deposition efficiency due to particle collisions.
Increased feed rates (up to 40.2 g/min) can stabilize particle trajectories.
High-dose powders are critical for treating lung infections or systemic diseases where large amounts of medication must reach the deep lungs. Delivered doses ≥is greater than or equal to Challenges: Fine particles (
Spray drying, milling, and spray-freeze drying are used to control the solid state and ensure stability.
In blasting operations, the refers to the amount of explosive (kg) needed to fracture a unit volume of rock. Excessive flow rates may decrease deposition efficiency due
Achieved by mixing different particle sizes (e.g., trimodal distributions) to fill voids.
Dispersibility, aerodynamic size (ideally 1–3 µm), and aerosolization stability. 🏗️ Manufacturing: High Flow & Density Delivered doses ≥is greater than or equal to
5 µm) have high cohesion forces, causing agglomeration and poor flow.