: Research on variant telomere sequences (tails of chromosomes) that can impact cell health and disease.
: This study identified EROS (encoded by the CYBC1 gene) as a protein essential for the expression of the NADPH oxidase components gp91phox and p22phox . Without EROS, these components are degraded, leading to a failure of the "respiratory burst" that helps immune cells kill bacteria. Significant Follow-up Research Eros.TAIL.1.var
: EROS is a selective chaperone regulating the phagocyte NADPH oxidase and purinergic signalling ( eLife , 2022). This paper clarifies that EROS acts as a molecular chaperone , binding to immature proteins to prevent their degradation and ensuring they are correctly processed within the cell. : Research on variant telomere sequences (tails of
: Eros is a novel transmembrane protein that controls the phagocyte respiratory burst and is essential for innate immunity Journal : Journal of Experimental Medicine (2017) Significant Follow-up Research : EROS is a selective