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For the best absorption, it is usually recommended to take the tablet on an empty stomach, either one hour before or two hours after a meal.
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Erythromycin (oral route) - Side effects & dosage - Mayo Clinic For the best absorption, it is usually recommended
It is highly effective for infections of the respiratory tract (like pneumonia or bronchitis), skin (including acne and rosacea), ears , nose , and throat . For the best absorption