iZotope maintains a research team that publishes scholarly papers on the underlying technologies used in their software, such as spectral processing and audio separation.
Note that there is a separate academic tool called IRIS 2+ used in solar physics research to recover radiative losses in the solar atmosphere. This is unrelated to the iZotope music software. Product Documentation and Version Details
Detailed operation for spectral filtering and sample-based synthesis is found in the iZotope Iris 2 Reference Manual . Free Download History (Advertisements)
Searching for a "paper" related to the advertisement of often leads to two different types of documents: technical research on spectral synthesis and product-related documentation or historical promotional deals. Technical Research and iZotope Papers