16748mp4

The team used HEK293 cells and techniques like fluorescence recovery after photobleaching (FRAP) to measure how fast proteins move within the cell. Where to Find the Paper and Videos Full Text (HTML/PDF): Available at eLife Sciences.

The researchers tracked the movement of the protein

-catenin into the nucleus in real-time. They found that while 16748mp4

-catenin subcellular dynamics and cyclin D1 mRNA transcription during Wnt signaling

The "mp4" suffix in your query likely refers to the (such as Video 2 ) included with this open-access research, which are available for download in MPEG-4 format. Paper Overview: Quantifying The team used HEK293 cells and techniques like

-catenin subcellular dynamics and cyclin D1 mRNA transcription during Wnt signaling" , which is identified by the digital object identifier (DOI) 10.7554/eLife.16748 .

The paper relies heavily on time-lapse movies to visualize these cellular dynamics. For example, Video 2 (referenced as part of eLife 16748) shows the accumulation and eventual egress of YFP- -catenin in cells treated with Wnt3a. They found that while -catenin subcellular dynamics and

-catenin levels rise steadily after activation, the actual transcription of the target gene ( CCND1 ) occurs in "bursts" rather than a constant stream.